Article

BioMedicine

, 4:8

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Personalized medicine in Type 2 Diabetes

  • Wen-Ling LiaoAffiliated withCenter for Personalized Medicine, China Medical University HospitalGraduate Institute of Integrated Medicine, China Medical University
  • , Fuu-Jen TsaiAffiliated withDepartment of Medical Research and Medical Genetics, China Medical University Hospital TaichungSchool of Chinese Medicine, China Medical UniversityDepartment of Pediatrics, China Medical University HospitalDepartment of Health and Nutrition Biotechnology, Asia UniversityDepartment of Medical Genetics, Pediatrics and Medical Research, China Medical University Hospital Email author 

Abstract

Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia, especially Taiwan, rising every year. The risk of developing T2D and diabetes complications is not only controlled by environmental but also by genetic factors. Genetic association studies have shown polymorphisms at specific loci may help identify individuals at greatest risk and response to oral antidiabetic drugs. This review probes effect of genetic profiling on T2D and its complications, using our study population as examples. Also, pharmacogenetics and pharmacogenomics of oral anitdiabetic drug will be explored.

Keywords

Genetic Pharmacogenetics Diabetes