Article

Biomedical Research and Therapy

, 1:11

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Adipose stem cells in the clinic

  • Phuc Van PhamAffiliated withLaboratory of Stem Cell Research and Application, University of Science, Vietnam National University Email author 

Abstract

Adipose-derived stem cells (ADSCs) are the most commonly used type of mesenchymal stem cell (MSC) in the clinic. ADSCs have some advantages in transplantation compared with MSCs from bone marrow and umbilical cord blood. ADSCs produce important growth factors for wound healing, modulate the immune system, decrease inflammation, and home to injured tissues. In particular, ADSC extraction from adipose tissue is a simple procedure with minimum invasiveness. Therefore, ADSCs have been evaluated in clinical trials and used in the treatment of many diseases. To date, ADSC transplantation has been approved in some countries to treat medical complications such as perianal pistula and osteoarthritis. This review provides an overview of the applications and future challenges of the use of ADSCs in clinical settings.

Keywords

Adipose-derived stem cells Stem cells Stem cell transplantation Cytotherapy Regenerative medicine