Case Report

Biomedical Research and Therapy

, 1:17

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Calretinin negative Paratesticular mesothelioma: a rare case report

  • Ankitha HebbarAffiliated withDeparment of Pathology, ESIC Medical College & PGIMSR
  • , Kalyani RajuAffiliated withDeparment of Pathology, ESIC Medical College & PGIMSR Email author 
  • , Srinivas Murthy VenkataramappaAffiliated withDeparment of Pathology, ESIC Medical College & PGIMSR


Malignant mesothelioma of the tunica vaginalis is rare. The etiology is unclear. Exposure to asbestos is attributed as one of the risk factor. It is commonly seen in the elderly age group with hydrocele as the presenting complaint. Diagnosis is usually confirmed following histopathological examination, marker studies by immunohistochemistry and electron microscopy. We present a case in a 54 year old male who presented with left scrotal swelling. Immunohistochemically the tumor cells were positive for WT1, keratins, EMA, vimentin and negative for calretinin, desmin, CEA and actin. Ours is a rare case of paratesticular mesothelioma with calretinin negative.


Calretinin marker Mesothelioma Paratesticular mesothelioma